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Molecular Biology Of The Transfer Rna Revisited

Molecular Biology Of The Transfer Rna Revisited
Author: Akio Kanai
Publisher: Frontiers E-books
ISBN: 2889193667
Size: 72.79 MB
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Transfer RNAs (tRNAs) are one of the classical non-coding RNAs whose lengths are approximately 70–100 bases. The secondary structure of tRNAs can be represented as the cloverleaf with 4 stems, and the three dimensional structure as an “L” shape. Historically, the basic function of tRNA as an essential component of translation was established in 1960s, i.e., each tRNA is charged with a target amino acid and these are delivered to the ribosome during protein synthesis. However, recent data suggests that the role of tRNA in cellular regulation goes beyond this paradigm. In most Archaea and Eukarya, precursor tRNAs are often interrupted by a short intron inserted strictly between the first and second nucleotide downstream of the anticodon, known as canonical nucleotide position (37/38). Recently, a number of reports describe novel aspects of tRNAs in terms of gene diversity, for example, several types of disrupted tRNA genes have been reported in the Archaea and primitive Eukarya, including multiple-intron-containing tRNA genes, split tRNA genes, and permuted tRNA genes. Our understanding of the enzymes involved in tRNA functions (e.g., aminoacyl-tRNA synthetase, tRNA splicing endonuclease, tRNA ligase) has deepened. Moreover, it is well known that tRNA possesses many types of base modifications whose enzymatic regulations remain to be fully elucidated. It was reported that impaired tRNA nuclear-cytoplasmic export links DNA damage and cell-cycle checkpoint. Furthermore, a variety of additional functions of tRNA, beyond its translation of the genetic code, have emerged rapidly. For instance, tRNA cleavage is a conserved part of the responses to a variety of stresses in eukaryotic cells. Age-associated or tissue-specific tRNA fragmentation has also been observed. Several papers suggested that some of these tRNA fragments might be involve in the cellular RNA interference (RNAi) system. These exciting data, have lead to this call for a Research Topic, that plans to revisit and summarize the molecular biology of tRNA. Beyond the topics outlined above, we have highlighted recent developments in bioinformatics tools and databases for tRNA analyses.
Molecular Biology of the Transfer RNA Revisited
Language: en
Pages:
Authors: Akio Kanai
Categories:
Type: BOOK - Published: 2014-12-19 - Publisher: Frontiers E-books
Transfer RNAs (tRNAs) are one of the classical non-coding RNAs whose lengths are approximately 70–100 bases. The secondary structure of tRNAs can be represented as the cloverleaf with 4 stems, and the three dimensional structure as an “L” shape. Historically, the basic function of tRNA as an essential component of
A Biography of Paul Berg
Language: en
Pages: 444
Authors: Errol C Friedberg
Categories: Science
Type: BOOK - Published: 2014-06-17 - Publisher: World Scientific
With a Foreword writer Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002) This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop
The Molecular and Physiological Basis of Nutrient Use Efficiency in Crops
Language: en
Pages: 512
Authors: Malcolm J. Hawkesford, Peter Barraclough
Categories: Technology & Engineering
Type: BOOK - Published: 2011-09-21 - Publisher: Wiley-Blackwell
Efforts to increase efficient nutrient use by crops are of growing importance as the global demand for food, fibre and fuel increases and competition for resources intensifies. The Molecular and Physiological Basis of Nutrient Use Efficiency in Crops provides both a timely summary of the latest advances in the field
Dissertation Abstracts International
Language: en
Pages:
Authors: Malcolm J. Hawkesford, Peter Barraclough
Categories: Dissertations, Academic
Type: BOOK - Published: 1987 - Publisher:
Books about Dissertation Abstracts International
Advances in Potato Chemistry and Technology
Language: en
Pages: 752
Authors: Jaspreet Singh, Lovedeep Kaur
Categories: Business & Economics
Type: BOOK - Published: 2016-01-19 - Publisher: Academic Press
Advances in Potato Chemistry and Technology, Second Edition, presents the latest knowledge on potato chemistry, including the identification, analysis, and uses of chemical components in potatoes. Beginning with a brief description of potato components, the book then delves into their role during processing, then presenting information on strategies for quality
Living Matter
Language: en
Pages: 160
Authors: Valery V. Stcherbic, Leonid P. Buchatsky
Categories: Science
Type: BOOK - Published: 2016-01-05 - Publisher: CRC Press
This book provides a review of biochemistry as an algebra of molecules of living matter and utilizes Clifford algebras to discuss the basic biochemical processes of DNA replication, DNA transcription, RNA splicing and translation. Viral carcinogenesis is discussed in depth, specific attention is paid to the structural features of biomolecules
Biology and Knowledge Revisited
Language: en
Pages: 176
Authors: Sue Taylor Parker, Jonas Langer, Constance Milbrath
Categories: Psychology
Type: BOOK - Published: 2014-04-04 - Publisher: Psychology Press
Based on the Annual Symposium of the Jean Piaget Society, Biology and Knowledge Revisited focuses on the classic issue of the relationship between nature and nurture in cognitive and linguistic development, and their neurological substrates. Contributors trace the history of ideas concerning the relationship between evolution and development, and bring
Trajectories of Genetics
Language: en
Pages: 266
Authors: Bernard Dujon, Georges Pelletier
Categories: Science
Type: BOOK - Published: 2020-04-09 - Publisher: John Wiley & Sons
As genetics becomes increasingly important in our everyday environment, misinterpretation of its scientific foundation leads to mixed feelings of hope and fear about the potential of its applications. Trajectories of Genetics uncovers the many facets of genetics - from humans to animals, plants, and the microscopic world through more than
Annual Review of Genetics
Language: en
Pages:
Authors: Bernard Dujon, Georges Pelletier
Categories: Genetics
Type: BOOK - Published: 2001 - Publisher:
Books about Annual Review of Genetics
Federation Proceedings
Language: en
Pages:
Authors: Federation of American Societies for Experimental Biology
Categories: Biology
Type: BOOK - Published: 1975 - Publisher:
Books about Federation Proceedings